Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9428901 | 0.84 | LMNA (0.57) | ALDH1A1LMNAHTTL3MBTL1GAA | |
| SCHEMBL9428907 | 0.83 | ALDH1A1 (0.35) | ALDH1A1LMNAHTTL3MBTL1POLB | |
| SCHEMBL28804378 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL28567613 | 0.77 | ALDH1A1 (0.37) | ALDH1A1LMNAHTTL3MBTL1POLB | |
| SCHEMBL9585593 | 0.76 | ALDH1A1 (0.50) | NPSR1ALDH1A1HTTPOLBTSHR | |
| SCHEMBL11496497 | 0.75 | ALDH1A1 (0.45) | ALDH1A1HTTTSHR | |
| SCHEMBL17413891 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNAHTTL3MBTL1GAA | |
| SCHEMBL2472140 | 0.73 | PTGS1 (0.68) | ALDH1A1LMNAPOLBPTGS1GAA | |
| SCHEMBL9593669 | 0.72 | ALDH1A1 (0.56) | NPSR1ALDH1A1LMNAHTTPOLB | |
| SCHEMBL2565733 | 0.72 | NPSR1 (0.36) | NPSR1ALDH1A1LMNAHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5276160-A | Amidation of primary or secondary amines | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-04 | — | — | US | disclosed |