Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 8/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PDE1A | P54750 | 1/20 | 0.33 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2809986 | 0.78 | PDE5A (0.43) | ALDH1A1HPGDPDE5AMTORMEN1 | |
| SCHEMBL2857871 | 0.74 | KMT2A (0.42) | ALDH1A1HPGDKDM4EMAPTPDE5A | |
| SCHEMBL3128161 | 0.73 | MTOR (0.44) | ALDH1A1HPGDPDE5AMTORMEN1 | |
| SCHEMBL28357438 | 0.73 | TERT (0.48) | ALDH1A1KDM4EMAPTPDE5AMTOR | |
| SCHEMBL4037518 | 0.73 | PDE5A (0.36) | ALDH1A1HPGDKDM4EPDE5AMTOR | |
| SCHEMBL3130798 | 0.72 | PDE5A (0.44) | ALDH1A1HPGDKDM4EPDE5AMTOR | |
| SCHEMBL28361193 | 0.72 | TERT (0.47) | ALDH1A1KDM4EMAPTPDE5AMTOR | |
| SCHEMBL7930957 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EMAPTPDE5A | |
| SCHEMBL4037512 | 0.67 | PDE5A (0.38) | ALDH1A1HPGDKDM4EPDE5AMTOR | |
| SCHEMBL5435892 | 0.67 | PDE5A (0.40) | ALDH1A1HPGDKDM4EMAPTPDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |