Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004360 | 0.95 | LMNA (0.30) | LMNATSHR | |
| SCHEMBL8927878 | 0.89 | TSHR (0.33) | LMNATSHR | |
| SCHEMBL5892589 | 0.86 | TSHR (0.40) | LMNATSHR | |
| SCHEMBL27586538 | 0.85 | TSHR (0.38) | TSHR | |
| SCHEMBL8393191 | 0.85 | CES2 (0.33) | TSHR | |
| SCHEMBL5898104 | 0.85 | — | — | |
| SCHEMBL626852 | 0.83 | — | — | |
| SCHEMBL9335673 | 0.82 | — | — | |
| SCHEMBL29291862 | 0.82 | TSHR (0.40) | TSHR | |
| SCHEMBL27498248 | 0.82 | CES2 (0.34) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728177-A | Aryl heterobicyclic compounds as Kv1.3 potassium Shaker channel blockers | D·E·萧尔研究有限责任公司 | 2022-07-08 | — | — | CN | disclosed |