Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.31 |
| ▸ | FDPS | P14324 | 8/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626852 | 0.93 | — | — | |
| SCHEMBL9335673 | 0.93 | — | — | |
| SCHEMBL27498248 | 0.93 | CES2 (0.34) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL8994354 | 0.91 | — | — | |
| SCHEMBL27882653 | 0.91 | TSHR (0.38) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL27496274 | 0.88 | — | — | |
| SCHEMBL25243973 | 0.87 | — | — | |
| SCHEMBL5898104 | 0.86 | — | — | |
| SCHEMBL9784038 | 0.85 | TSHR (0.42) | CES2LPAR1LPAR3TSHRTHRB | |
| SCHEMBL28806069 | 0.85 | LMNA (0.30) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741297-A | Nanoparticles | UNIV KOREA RES & BUS FOUND | 2012-10-17 | — | — | CN | disclosed |
| EP-0912592-A1 | PHOSPHOTRIESTER OLIGONUCLEOTIDES, AMIDITES AND METHOD OF PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998005961-A1 | COMPOUNDS HAVING A PLURALITY OF NITROGENOUS SUBSTITUENTS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |
| WO-1997047637-A1 | PHOSPHOTRIESTER OLIGONUCLEOTIDES, AMIDITES AND METHOD OF PREPARATION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (US) | 1997-12-18 | — | — | WO | disclosed |