Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | ABL2 | P42684 | 1/20 | 0.52 |
| ▸ | TTK | P33981 | 2/20 | 0.51 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.49 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.49 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.49 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.49 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.48 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | LIPC | P11150 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16899860 | 0.89 | MET (0.52) | METTTKGPR119FGFR3KDR | |
| SCHEMBL1653749 | 0.88 | TNK2 (0.56) | METEGFRSRCGPR119FGFR3 | |
| SCHEMBL30701907 | 0.86 | CCNC (0.51) | METTTKGPR119FGFR3KDR | |
| SCHEMBL16899801 | 0.84 | MET (0.51) | METTTKGPR119FGFR3KDR | |
| SCHEMBL20280701 | 0.84 | MET (0.52) | METTTKGPR119FGFR3KDR | |
| SCHEMBL15431560 | 0.84 | GPR119 (0.55) | METTTKGPR119FGFR3KDR | |
| SCHEMBL16899750 | 0.83 | MET (0.51) | METTTKGPR119FGFR3KDR | |
| SCHEMBL15416610 | 0.83 | MET (0.53) | METTTKGPR119FGFR3KDR | |
| SCHEMBL16907836 | 0.83 | MET (0.51) | METTTKGPR119FGFR3KDR | |
| SCHEMBL20135336 | 0.83 | GPR119 (0.58) | METTTKGPR119TNK2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554936-A1 | CRIZOTINIB ANALOGUES AS SHIP1 INHIBITORS USEFUL TO TREAT ALZHEINER'S DISEASES | The Trustees of Indiana University (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024015759-A1 | CRIZOTINIB ANALOGUES AS SHIP1 INHIBITORS USEFUL TO TREAT ALZHEINER'S DISEASES | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-01-18 | — | — | WO | disclosed |
| CN-103420906-A | Novel tyrosine protein kinase inhibitor | NANJING SANHOME PHARMACEUTICAL CO LTD | 2013-12-04 | — | — | CN | disclosed |