Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.38 |
| ▸ | LOX | P28300 | 3/20 | 0.38 |
| ▸ | UTRN | P46939 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536253 | 0.86 | HCRTR1 (0.40) | HCRTR1HCRTR2LOXL2LOXUTRN | |
| SCHEMBL30329140 | 0.79 | RECQL (0.47) | HCRTR1HCRTR2LOXL2LOXUTRN | |
| SCHEMBL18083206 | 0.79 | NOS3 (0.47) | HCRTR1HCRTR2LOXL2LOXUTRN | |
| SCHEMBL1437199 | 0.79 | RECQL (0.47) | HCRTR1HCRTR2LOXL2LOXUTRN | |
| SCHEMBL14925194 | 0.79 | HCRTR1 (0.40) | HCRTR1HCRTR2LOXL2LOXUTRN | |
| SCHEMBL13164105 | 0.79 | LOXL2 (0.61) | HCRTR1HCRTR2LOXL2LOX | |
| Hydrochloric Acid SCHEMBL25210344 | 0.78 | LOXL2 (0.59) | HCRTR1HCRTR2LOXL2LOX | |
| SCHEMBL14486857 | 0.77 | LOXL2 (0.62) | LOXL2LOXGRM2TDP1 | |
| SCHEMBL31583016 | 0.77 | LOXL2 (0.62) | LOXL2LOXGRM2TDP1 | |
| SCHEMBL17000198 | 0.77 | LOXL2 (0.41) | HCRTR1HCRTR2LOXL2LOXUTRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201261-A | Lactam derivatives as orexin receptor antagonists | ACTELION PHARMACEUTICALS LTD | 2013-07-10 | — | — | CN | disclosed |