Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 5/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.40 |
| ▸ | F13A1 | P00488 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | TGM1 | P22735 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28805178 | 0.81 | CASP3 (0.49) | CASP3CASP7CASP1CASP9CA12 | |
| SCHEMBL27605812 | 0.68 | PARG (0.40) | LMNAMAPT | |
| SCHEMBL27889639 | 0.66 | GAA (0.59) | MAPT | |
| SCHEMBL27913253 | 0.63 | CASP3 (0.41) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL27642279 | 0.62 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL14111820 | 0.62 | ALDH1A1 (0.57) | CASP7CASP1ALDH1A1KDM4ELMNA | |
| SCHEMBL29857922 | 0.62 | PLD1 (0.73) | ALDH1A1KDM4EMAPTHSD17B10POLB | |
| SCHEMBL15800694 | 0.62 | PLD1 (0.73) | ALDH1A1KDM4EMAPTHSD17B10POLB | |
| SCHEMBL21353591 | 0.62 | — | — | |
| SCHEMBL458636 | 0.61 | CA12 (0.69) | CASP3CASP7CASP1CASP9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183631-A | Novel isatin-5-sulfonamide derivative and application of same in preparation of medicines used for treating atypical pneumonia | TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE | 2013-07-03 | — | — | CN | disclosed |