Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 10/20 | 0.41 |
| ▸ | CASP7 | P55210 | 7/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP4 | P49662 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27605812 | 0.82 | PARG (0.40) | — | |
| SCHEMBL28805178 | 0.78 | CASP3 (0.49) | CASP3CASP7CASP1CASP9 | |
| SCHEMBL27951598 | 0.77 | CHRM2 (0.36) | — | |
| SCHEMBL28086690 | 0.75 | CASP7 (0.53) | CASP3CASP7CASP1 | |
| SCHEMBL27593641 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL27593507 | 0.75 | CHRM2 (0.39) | CASP7CASP1 | |
| SCHEMBL27788104 | 0.74 | CHRM2 (0.50) | — | |
| SCHEMBL28813536 | 0.74 | ALDH1A1 (0.36) | — | |
| SCHEMBL27669965 | 0.73 | ADRA2C (0.42) | — | |
| SCHEMBL27845916 | 0.72 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103183631-A | Novel isatin-5-sulfonamide derivative and application of same in preparation of medicines used for treating atypical pneumonia | TIANJIN INT JOINT ACADEMY BIOTECHNOLOGY & MEDICINE | 2013-07-03 | — | — | CN | disclosed |