Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.78 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.61 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.61 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.60 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | GRM5 | P41594 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23286796 | 0.87 | KMT2A (0.77) | RXFP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL29738098 | 0.87 | KMT2A (0.77) | RXFP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28808130 | 0.86 | CHRNB2 (0.60) | RXFP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3499621 | 0.81 | CHRNB2 (0.59) | RXFP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL26310094 | 0.81 | KMT2A (0.60) | RXFP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28937135 | 0.81 | RXFP1 (0.78) | RXFP1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28327587 | 0.81 | RXFP1 (0.78) | RXFP1CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL28808136 | 0.79 | HTR1F (0.57) | RXFP1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL28937139 | 0.77 | RXFP1 (0.71) | RXFP1NPC1RAB9AKMT2AMEN1 | |
| SCHEMBL10068144 | 0.77 | RXFP1 (0.71) | RXFP1NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728929-A | Pyridine methylene piperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |