Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.53 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GRM5 | P41594 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | FLT4 | P35916 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808156 | 0.86 | HTR1F (0.56) | HTR1FRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL28937119 | 0.84 | HTR1F (0.63) | HTR1FRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL28589018 | 0.82 | MEN1 (0.49) | HTR1FKMT2AALDH1A1SORT1HPGD | |
| SCHEMBL29737990 | 0.81 | PKM (0.57) | SMN1; SMN2KMT2AALDH1A1LMNAGAA | |
| SCHEMBL23287012 | 0.81 | PKM (0.57) | SMN1; SMN2KMT2AALDH1A1LMNAGAA | |
| SCHEMBL28937129 | 0.81 | HTR1F (0.62) | HTR1FRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL28808121 | 0.79 | RXFP1 (0.78) | HTR1FRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL16321125 | 0.76 | MEN1 (0.78) | RAB9ANPC1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL28809348 | 0.75 | MEN1 (0.62) | HTR1FRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL23528936 | 0.75 | HTR1F (0.75) | HTR1FRAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728929-A | Pyridine methylene piperidine derivatives and use thereof | 广东东阳光药业有限公司 | 2022-07-08 | — | — | CN | disclosed |