SCHEMBL2880822

SCHEMBL2880822

C=C(C)C(=O)NC(C)c1ccc(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)S(=O)(=O)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 2/20 0.40
CXCR1 P25024 1/20 0.37
CNR1 P21554 3/20 0.37
ACACB O00763 13/20 0.36
ACACA Q13085 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2881973 0.87 CXCR2 (0.40) CXCR2CXCR1CNR1ACACBACACA
SCHEMBL2742193 0.81 RXFP1 (0.43)
SCHEMBL9966138 0.80 CXCR2 (0.38) CXCR2CXCR1
SCHEMBL15082411 0.79 CXCR2 (0.44) CXCR2CXCR1
SCHEMBL2742190 0.78 ELANE (0.44) CXCR2CXCR1
SCHEMBL2742220 0.77 STS (0.46) ACACB
SCHEMBL10204305 0.74 HDAC3 (0.39)
SCHEMBL682247 0.74 ALDH1A1 (0.43) CXCR2CXCR1
SCHEMBL12039866 0.74 EGFR (0.35) CXCR2CXCR1
SCHEMBL10233233 0.73 ELANE (0.34) CXCR2CXCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120034559-A1 ACTINIC-RAY- OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM THEREFROM AND METHOD OF FORMING PATTERN THEREWITH FUJIFILM CORPORATION (JP) 2012-02-09 US disclosed
US-20120003583-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, AND RESIST FILM AND PATTERN FORMING METHOD USING THE COMPOSITION FUJIFILM CORPORATION (JP) 2012-01-05 US disclosed