Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 4/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 5/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563920 | 0.84 | CYP19A1 (0.46) | CYP19A1CA2TRPV4P2RX7CHKA | |
| SCHEMBL742533 | 0.84 | CYP19A1 (0.46) | CYP19A1CA2TRPV4P2RX7CHKA | |
| Hydrazine SCHEMBL4301523 | 0.81 | HSP90AA1 (0.44) | CYP19A1CA2TRPV4P2RX7CHKA | |
| Phenol SCHEMBL27642567 | 0.79 | L3MBTL1 (0.52) | CA2TDP1CA12CA1GLA | |
| SCHEMBL27739448 | 0.77 | CYP19A1 (0.36) | CYP19A1LMNATRPV4 | |
| Phenol SCHEMBL27752817 | 0.75 | CA12 (0.48) | CYP19A1CA2TDP1CA12CA1 | |
| SCHEMBL27617622 | 0.75 | ALOX5AP (0.39) | CYP19A1CA2SYKLMNAPOLB | |
| Piperazine SCHEMBL4824527 | 0.74 | ADRB1 (0.46) | CYP19A1CA2TRPV4CHKAHSP90AA1 | |
| Butyl Alcohol SCHEMBL27471687 | 0.71 | CYP2D6 (0.39) | CYP19A1TRPV4P2RX7PTGS1 | |
| Phenol SCHEMBL6896776 | 0.71 | CA12 (0.61) | CA2TDP1CA12CA1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103387546-A | Method for preparing 2-(2,4-dichloroanilino)-6-trifluoromethylpyrimidylphenol | SINOCHEM CORP | 2013-11-13 | — | — | CN | claimed |
| CN-103387546-A | Method for preparing 2-(2,4-dichloroanilino)-6-trifluoromethylpyrimidylphenol | SINOCHEM CORP | 2013-11-13 | — | — | CN | disclosed |