SCHEMBL28808595

SCHEMBL28808595

CCCCCCN(C(=O)OC(C)(C)C)C(Cc1ccc(O)cc1)C(=O)OCC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.36
PTGS2 P35354 3/20 0.36
ADRA2A P08913 2/20 0.36
ADORA3 P0DMS8 2/20 0.36
TACR2 P21452 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
SLC6A3 Q01959 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
SHBG P04278 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
HSPD1 P10809 1/20 0.36
ADRB3 P13945 1/20 0.36
HTR2C P28335 1/20 0.36
HSPE1 P61604 1/20 0.36
HIF1A Q16665 1/20 0.36
TST Q16762 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7273415 0.91 ESR1 (0.41) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL28370126 0.91 ESR1 (0.41) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL7280647 0.91 ESR1 (0.41) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL7280562 0.89 L3MBTL1 (0.39) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL28365896 0.89 L3MBTL1 (0.39) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL7273178 0.89 L3MBTL1 (0.39) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL28365893 0.89 L3MBTL1 (0.39) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL7282010 0.84 HDAC8 (0.33) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL7272828 0.84 HDAC8 (0.33) ESR1PTGS2ADRA2AADORA3TACR2
SCHEMBL28017919 0.84 CTSK (0.40) ESR1L3MBTL1CTSSCTSKHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102432491-B Gelling agent based on tyrosine derivative and application thereof UNIV XI AN SCI & TECHNOLOGY 2013-10-23 CN disclosed