SCHEMBL7273178

SCHEMBL7273178

CCCCCCCCN(C(=O)OC(C)(C)C)[C@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.39
CTSS P25774 1/20 0.39
CTSK P43235 1/20 0.39
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
HSPD1 P10809 1/20 0.38
ADRB3 P13945 1/20 0.38
HTR2C P28335 1/20 0.38
HSPE1 P61604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7280562 1.00 L3MBTL1 (0.39) L3MBTL1CTSSCTSKESR1ADRA2A
SCHEMBL28365896 1.00 L3MBTL1 (0.39) L3MBTL1CTSSCTSKESR1ADRA2A
SCHEMBL28365893 1.00 L3MBTL1 (0.39) L3MBTL1CTSSCTSKESR1ADRA2A
SCHEMBL28017919 0.95 CTSK (0.40) L3MBTL1CTSSCTSKESR1HDAC3
SCHEMBL23859851 0.91 L3MBTL1 (0.46) L3MBTL1CTSKHDAC3HDAC1HDAC2
SCHEMBL23859850 0.91 L3MBTL1 (0.46) L3MBTL1CTSKHDAC3HDAC1HDAC2
SCHEMBL29226532 0.90 PPARG (0.41) L3MBTL1CTSSCTSK
SCHEMBL7273415 0.89 ESR1 (0.41) L3MBTL1CTSSCTSKESR1ADRA2A
SCHEMBL28370126 0.89 ESR1 (0.41) L3MBTL1CTSSCTSKESR1ADRA2A
SCHEMBL28808595 0.89 ESR1 (0.36) L3MBTL1CTSSCTSKESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0462531-B1 Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain FUJISAWA PHARMACEUTICAL CO (JP) 1996-10-02 EP disclosed
EP-0729974-A1 Cyclic polypeptide with antibiotic activity and a process for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-09-04 EP disclosed
EP-0462531-A2 Cyclic polypeptide with antibiotic activity, process for its preparation and pure culture of a Coelomycetes strain FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-12-27 EP disclosed