Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | GCGR | P47871 | 10/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ULK1 | O75385 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28808159 | 0.86 | VEGFA (0.30) | EGLN1 | |
| SCHEMBL20921637 | 0.85 | KDM4E (0.32) | — | |
| SCHEMBL28808904 | 0.83 | CA1 (0.35) | ULK1 | |
| SCHEMBL12449485 | 0.82 | MAP4K4 (0.38) | EGLN1 | |
| SCHEMBL28808899 | 0.82 | PREP (0.35) | — | |
| SCHEMBL29700184 | 0.81 | KCNH2 (0.38) | HIF1AGCGREGLN1 | |
| SCHEMBL28808185 | 0.81 | BACE1 (0.34) | — | |
| SCHEMBL29724107 | 0.81 | BACE1 (0.34) | — | |
| SCHEMBL28808906 | 0.81 | — | — | |
| SCHEMBL737905 | 0.80 | ULK1 (0.39) | ULK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853748-A | Trifluoromethyl-containing isoxazoline derivative, and preparation method and application thereof | 武汉工程大学 | 2022-08-05 | — | — | CN | disclosed |