Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ULK1 | O75385 | 4/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15999838 | 0.93 | HDAC4 (0.37) | ULK1GABRA5ALDH1A1MAPTCYP3A4 | |
| SCHEMBL738000 | 0.89 | ULK1 (0.36) | ULK1GABRA5JAK2JAK1JAK3 | |
| SCHEMBL738168 | 0.88 | ULK1 (0.39) | ULK1GABRA5MAPTJAK2JAK1 | |
| SCHEMBL119374 | 0.88 | PTGES (0.35) | ULK1GABRA5ALDH1A1MAPT | |
| SCHEMBL1860843 | 0.87 | PPARA (0.46) | SMN1; SMN2KMT2A | |
| SCHEMBL19775268 | 0.87 | KDM4E (0.34) | ALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL1863968 | 0.86 | SMN1; SMN2 (0.52) | MAPTJAK1SMN1; SMN2KMT2A | |
| SCHEMBL23874308 | 0.86 | TAOK1 (0.37) | ULK1GABRA5ALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL38653211 | 0.86 | CACNA1H (0.37) | ALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL739005 | 0.86 | F10 (0.34) | ULK1GABRA5ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-21 | — | — | US | disclosed |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-24 | — | — | US | disclosed |
| US-20180318266-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-11-08 | — | — | US | disclosed |
| US-20170065565-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2017-03-09 | — | — | US | disclosed |
| EP-1731512-B9 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | NISSAN CHEMICAL IND LTD (JP) | 2017-03-01 | — | — | EP | disclosed |
| US-9023836-B2 | Use of substituted heterocyclic compounds to control sea lice on fish | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-9023836-B2 | Use of substituted heterocyclic compounds to control sea lice on fish | NOVARTIS TIERGESUNDHEIT AG (CH) | 2015-05-05 | — | — | US | disclosed |
| US-20150105398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL CORPORATION (JP) | 2015-04-16 | — | — | US | disclosed |
| US-20130095126-A1 | USE OF SUBSTITUTED HETEROCYCLIC COMPOUNDS TO CONTROL SEA LICE ON FISH | NOVARTIS TIERGESUNDHEIT AG (CH) | 2013-04-18 | — | — | US | disclosed |
| US-20120172615-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-05 | — | — | US | disclosed |
| US-8138213-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-20 | — | — | US | disclosed |
| WO-2011157733-A2 | NEW USE | NOVARTIS AG (CH) | 2011-12-22 | — | — | WO | disclosed |
| US-20110251398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-10-13 | — | — | US | disclosed |
| US-8022089-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2011-09-20 | — | — | US | disclosed |
| US-7662972-B2 | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2009-12-17 | — | — | US | disclosed |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-03-22 | — | — | US | disclosed |
| EP-1731512-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND NOXIOUS ORGANISM CONTROL AGENT | Nissan Chemical Industries, Ltd. (JP) | 2006-12-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | ULK1 4822/4885GABRA5 440/4885ALDH1A1 3263/4885 |
| US-20230355590-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | HDAC7, ACHE, BRDT | ULK1 4300/4885GABRA5 27/4885ALDH1A1 865/4885 |
| US-10596157-B2 | Isoxazoline-substituted benzamide compound and pesticide | CHRM3, C3AR1, C9 | ULK1 4847/4885GABRA5 351/4885ALDH1A1 3052/4885 |
| US-20120172615-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | ULK1 4802/4885GABRA5 572/4885ALDH1A1 3702/4885 |
| US-20180318266-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | CHRM3, C3AR1, C9 | ULK1 4847/4885GABRA5 351/4885ALDH1A1 3052/4885 |
| US-20090312330-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | ATM, CHRM1, NAT1 | ULK1 4476/4885GABRA5 980/4885ALDH1A1 806/4885 |
| US-10874645-B2 | Isoxazoline-substituted benzamide compound and pesticide | C3AR1, C5, C9 | ULK1 4822/4885GABRA5 403/4885ALDH1A1 3404/4885 |
| US-20130095126-A1 | USE OF SUBSTITUTED HETEROCYCLIC COMPOUNDS TO CONTROL SEA LICE ON FISH | TYR, NISCH, GYPA | ULK1 4264/4885GABRA5 915/4885ALDH1A1 905/4885 |
| US-20110251398-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | CBR3, CHRM1, CBR1 | ULK1 4809/4885GABRA5 201/4885ALDH1A1 1983/4885 |
| US-20170065565-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | ULK1 4823/4885GABRA5 411/4885ALDH1A1 3048/4885 |
| US-20070066617-A1 | Insecticidal and acaricidal activity for many agricultural insect pests, spider mites; endo- or ecto-parasiticide for mammals or birds; veterinary medicine; environmentally friendly | CHRM1, DDT, ATM | ULK1 2728/4885GABRA5 1938/4885ALDH1A1 1359/4885 |
| US-20200155511-A1 | ISOXAZOLINE-SUBSTITUTED BENZAMIDE COMPOUND AND PESTICIDE | C3AR1, C5, C9 | ULK1 4822/4885GABRA5 403/4885ALDH1A1 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.