Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28806937 | 0.90 | TP53 (0.57) | TP53LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL11898237 | 0.77 | LMNA (0.64) | TP53LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL7593020 | 0.75 | TP53 (0.67) | TP53LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL21643747 | 0.74 | TSHR (0.55) | DRD2TBXA2RRAB9ANPC1 | |
| SCHEMBL27915823 | 0.70 | LMNA (0.77) | TP53LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL4688122 | 0.69 | RECQL (0.60) | TP53LMNAMAPTMEN1KMT2A | |
| SCHEMBL26597943 | 0.69 | TP53 (0.52) | TP53LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL19714625 | 0.68 | TP53 (0.62) | TP53LMNASMN1; SMN2MAPTMEN1 | |
| SCHEMBL21643773 | 0.68 | DRD2 (0.72) | TP53LMNASMN1; SMN2KMT2ADRD2 | |
| SCHEMBL16940824 | 0.68 | TP53 (0.50) | TP53LMNASMN1; SMN2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450093-A | 2-aminobenzimidazoles and applications thereof | UNIV CHINA PHARMA | 2013-12-18 | — | — | CN | claimed |
| CN-103450093-A | 2-aminobenzimidazoles and applications thereof | UNIV CHINA PHARMA | 2013-12-18 | — | — | CN | disclosed |