Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677959 | 0.83 | HSD17B10 (0.56) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL448111 | 0.82 | HSD17B10 (0.50) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL28551166 | 0.81 | HSD17B10 (0.54) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL6671840 | 0.79 | HSD17B10 (0.56) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL1538287 | 0.79 | HSD17B10 (0.56) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL397351 | 0.79 | HSD17B10 (0.56) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL27579582 | 0.78 | HSD11B1 (0.54) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL5180046 | 0.76 | ALDH1A1 (0.52) | HSD17B10ACHECA1CA2CA5A | |
| SCHEMBL426201 | 0.76 | HSD17B10 (0.44) | HSD17B10ACHEHSD11B1CA1CA2 | |
| SCHEMBL677900 | 0.75 | HSD17B10 (0.52) | HSD17B10ACHEHSD11B1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103534241-A | Fak inhibitor | CANCER THERAPEUTICS CRC PTY LTD | 2014-01-22 | — | — | CN | disclosed |