Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA3 | P07451 | 2/20 | 0.45 |
| ▸ | CA4 | P22748 | 2/20 | 0.45 |
| ▸ | CA6 | P23280 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28551166 | 0.88 | HSD17B10 (0.54) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL6671840 | 0.86 | HSD17B10 (0.56) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL397351 | 0.86 | HSD17B10 (0.56) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL1538287 | 0.86 | HSD17B10 (0.56) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL27579582 | 0.85 | HSD11B1 (0.54) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL5180046 | 0.83 | ALDH1A1 (0.52) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL28809138 | 0.83 | HSD17B10 (0.48) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL11453501 | 0.82 | HSD17B10 (0.52) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL1023276 | 0.82 | HSD11B1 (0.60) | HSD17B10ACHEALDH1A1CA1CA2 | |
| SCHEMBL2145337 | 0.82 | HSD17B10 (0.52) | HSD17B10ACHEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111943906-B | Amidine derivatives, preparation method, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-111943906-A | Amidine derivative, preparation method thereof, pharmaceutical composition and application | 中国医学科学院药物研究所 | 2020-11-17 | — | — | CN | disclosed |
| EP-1619211-B1 | PROCESS FOR PRODUCTION OF LIVING-RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL CO LTD (JP) | 2012-10-17 | — | — | EP | disclosed |
| US-20110275774-A1 | ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER | YAMAGO SHIGERU | 2011-11-10 | — | — | US | disclosed |
| EP-1595894-B1 | PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS | OTSUKA CHEMICAL CO LTD (JP) | 2011-10-12 | — | — | EP | disclosed |
| US-8008414-B2 | Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-08-30 | — | — | US | disclosed |
| EP-1767539-B1 | ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER | OTSUKA CHEMICAL CO LTD (JP) | 2011-07-27 | — | — | EP | disclosed |
| CN-1820030-B | Process for the production of living radical polymers and polymers | OTSUKA CHEMICAL CO LTD | 2010-10-06 | — | — | CN | disclosed |
| US-7662899-B2 | Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-02-16 | — | — | US | disclosed |
| US-20090318546-A1 | Chromen-2-One Derivatives | NOVARTIS AG (CH) | 2009-12-24 | — | — | US | disclosed |
| EP-1595894-A1 | PROCESS FOR THE PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2005-11-16 | — | — | EP | disclosed |
| US-20050245714-A1 | Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer | OTSUKA CHEMICAL CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| CN-1675253-A | Method for producing living radical polymer and polymer | OTSUKA CHEMICAL CO LTD (JP) | 2005-09-28 | — | — | CN | disclosed |
| CN-1649838-A | Organic tellurium compound, method for producing same, living radical polymerization initiator, method for producing polymer using same, and polymer | OTSUKA KAGAKU KK (JP) | 2005-08-03 | — | — | CN | disclosed |
| EP-1541550-A1 | ORGANIC TELLURIUM COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH THE SAME, AND POLYMER | Otsuka Chemical Co., Ltd. (JP) | 2005-06-15 | — | — | EP | disclosed |
| EP-1541592-A1 | PROCESS FOR PRODUCTION OF LIVING RADICAL POLYMERS AND POLYMERS | OTSUKA CHEMICAL COMPANY, LIMITED (JP) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004085421-A2 | BIOREDUCTIVELY-ACTIVATED PRODRUGS | ANGIOGENE PHARMACEUTICALS LIMITED (GB) | 2004-10-07 | — | — | WO | disclosed |
| EP-0121192-B1 | ANALYTICAL TEST COMPOSITION, DEVICE, METHOD FOR ITS PREPARATION AND METHOD FOR THE DETERMINATION OF PEROXIDATIVELY ACTIVE SUBSTANCE | MILES INC. (US) | 1990-06-27 | — | — | EP | disclosed |
| EP-0121192-A2 | Analytical test composition, device, method for its preparation and method for the determination of peroxidatively active substance | MILES INC. (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4447542-A | USING SUBSTITUTED CUMENE HYDROPEROXIDE AND INDICATOR; COLORIMETRIC ANALYSIS | MILES LABORATORIES, INC. (US) | 1984-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245714-A1 | Organic tellurium compound, process for producing the same, living radical polymerization initiator, process for producing polymer with the same, and polymer | ODC1, TERB1, TTI1 | HSD17B10 801/4885ACHE 371/4885ALDH1A1 1201/4885 |
| US-20090318546-A1 | Chromen-2-One Derivatives | CYP1A2, CYP4B1, CYP1B1 | HSD17B10 351/4885ACHE 2700/4885ALDH1A1 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.