Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27937736 | 0.85 | ADORA3 (0.56) | PPARGLMNAABCC8TSHRBLM | |
| Glyburide SCHEMBL7833374 | 0.82 | NLRP3 (0.95) | PPARGLMNAABCC8TSHRBLM | |
| SCHEMBL2615504 | 0.81 | PPARG (0.84) | PPARGLMNAABCC8TSHRBLM | |
| SCHEMBL30577313 | 0.81 | PDE4A (0.66) | PPARGLMNAABCC8TSHRBLM | |
| SCHEMBL16389010 | 0.81 | PPARG (0.82) | PPARGLMNAABCC8TSHRBLM | |
| SCHEMBL13952232 | 0.80 | PPARG (0.81) | PPARGLMNAABCC8TSHRBLM | |
| Glyburide SCHEMBL15669346 | 0.80 | NLRP3 (1.00) | PPARGLMNAABCC8TSHRBLM | |
| Glyburide SCHEMBL8497112 | 0.80 | NLRP3 (1.00) | PPARGLMNAABCC8TSHRBLM | |
| Glyburide SCHEMBL22009 | 0.80 | NLRP3 (1.00) | PPARGLMNAABCC8TSHRBLM | |
| SCHEMBL2631551 | 0.80 | PPARG (0.81) | PPARGLMNAABCC8TSHRBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103415286-A | Compounds and methods for treating pain | AKRON MOLECULES GMBH | 2013-11-27 | — | — | CN | disclosed |