Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 9/20 | 0.50 |
| ▸ | TBK1 | Q9UHD2 | 9/20 | 0.50 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29753944 | 1.00 | IKBKE (0.50) | IKBKETBK1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29754041 | 0.81 | IKBKE (0.60) | IKBKETBK1NR4A2ROCK1ROCK2 | |
| SCHEMBL28809170 | 0.81 | IKBKE (0.60) | IKBKETBK1NR4A2ROCK1ROCK2 | |
| SCHEMBL23534329 | 0.81 | DYRK1A (0.58) | PRKAA1 | |
| SCHEMBL29754046 | 0.79 | IKBKE (0.59) | IKBKETBK1NR4A2ROCK1 | |
| SCHEMBL28809188 | 0.79 | IKBKE (0.59) | IKBKETBK1NR4A2ROCK1 | |
| SCHEMBL28810253 | 0.78 | IKBKE (0.55) | IKBKETBK1NR4A2ROCK1ROCK2 | |
| SCHEMBL29754120 | 0.78 | IKBKE (0.55) | IKBKETBK1NR4A2ROCK1ROCK2 | |
| SCHEMBL28809248 | 0.77 | IKBKE (0.50) | IKBKETBK1NR4A2ROCK1ROCK2 | |
| SCHEMBL29753935 | 0.77 | IKBKE (0.50) | IKBKETBK1NR4A2ROCK1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114867718-A | Novel indazole derivative and use thereof | 韩国化学研究院 | 2022-08-05 | — | — | CN | disclosed |