Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 10/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810410 | 0.86 | DHODH (0.52) | RORCKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL28809982 | 0.85 | KDM4E (0.47) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL13170473 | 0.79 | KDM4E (0.61) | KDM4ELMNAPOLBMAPK1NPSR1 | |
| SCHEMBL13170385 | 0.79 | KDM4E (0.61) | KDM4ELMNAPOLBMAPK1NPSR1 | |
| SCHEMBL4631887 | 0.75 | KDM4E (0.56) | RORCKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL4631890 | 0.75 | KDM4E (0.56) | RORCKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL28811113 | 0.75 | MAPT (0.45) | KDM4ELMNAMAPK1NPSR1DHODH | |
| SCHEMBL8964807 | 0.74 | TP53 (0.49) | RORCKDM4ELMNAPOLBMAPK1 | |
| SCHEMBL27619336 | 0.72 | KDM4E (0.55) | KDM4ELMNAPOLBMAPK1NPSR1 | |
| SCHEMBL8921074 | 0.71 | KDM4E (0.53) | KDM4ELMNAPOLBMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970622-B | 2-substituent-3- (9-alkyl-9H-carbazole-3-yl) acrylonitrile compound and preparation method thereof | 陕西科技大学 | 2022-06-07 | — | — | CN | disclosed |