Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810410 | 0.89 | DHODH (0.52) | MAPTTDP1DHODHKDM4ENPSR1 | |
| SCHEMBL28809982 | 0.84 | KDM4E (0.47) | MAPTKDM4EHPGDTSHRNPC1 | |
| SCHEMBL8050356 | 0.76 | ALDH1A1 (0.48) | MAPTATMKDM4EL3MBTL1HPGD | |
| SCHEMBL5317693 | 0.76 | ALDH1A1 (0.48) | MAPTATMKDM4EL3MBTL1HPGD | |
| SCHEMBL28809379 | 0.75 | RORC (0.48) | MAPTDHODHPKMKDM4ENPSR1 | |
| SCHEMBL16218971 | 0.74 | TTR (0.46) | MAPTKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL4580067 | 0.74 | ATM (0.48) | MAPTTDP1ATMKDM4ENPSR1 | |
| SCHEMBL2582174 | 0.74 | HSD17B1 (0.46) | TDP1DHODHKDM4EL3MBTL1HPGD | |
| SCHEMBL14111461 | 0.73 | CA12 (0.55) | MAPTKDM4EHPGDALDH1A1HSD17B10 | |
| SCHEMBL7608324 | 0.73 | CA12 (0.55) | MAPTKDM4EHPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109970622-B | 2-substituent-3- (9-alkyl-9H-carbazole-3-yl) acrylonitrile compound and preparation method thereof | 陕西科技大学 | 2022-06-07 | — | — | CN | disclosed |