Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25425019 | 0.89 | — | — | |
| SCHEMBL28810402 | 0.75 | ALDH1A1 (0.33) | ALDH1A1LMNASLC18A3HCAR1 | |
| SCHEMBL28810398 | 0.75 | ABCB1 (0.35) | MEN1KMT2AALDH1A1HTTPKM | |
| SCHEMBL28810606 | 0.75 | SLC18A3 (0.32) | MAPK1HTTSLC18A3NPC1RAB9A | |
| SCHEMBL19626479 | 0.75 | ALDH1A1 (0.33) | ALDH1A1LMNASLC18A3HCAR1 | |
| SCHEMBL28810408 | 0.73 | SLC18A3 (0.46) | ALDH1A1NPSR1LMNAHTTSLC18A3 | |
| SCHEMBL28810749 | 0.72 | CDK5 (0.33) | ALDH1A1LMNASLC18A3 | |
| SCHEMBL19625277 | 0.71 | HSD11B1 (0.37) | MEN1KMT2AALDH1A1NPSR1LMNA | |
| SCHEMBL10406327 | 0.71 | DRD2 (0.56) | KMT2AALDH1A1LMNAHTTDRD2 | |
| SCHEMBL28810759 | 0.71 | HRH3 (0.42) | ALDH1A1HRH3DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |