Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27951818 | 0.78 | MAOB (0.43) | ALDH1A1L3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL2330819 | 0.76 | GABRP (0.36) | ALDH1A1SMYD3LOXL2IGF1RCYP4F2 | |
| SCHEMBL27939553 | 0.75 | KDM5C (0.39) | NPC1RAB9AMEN1TSHRKMT2A | |
| SCHEMBL2330813 | 0.75 | CYP4F2 (0.38) | ALDH1A1IGF1RCYP4F2CYP4A11TSHR | |
| SCHEMBL1167120 | 0.72 | RECQL (0.50) | ALDH1A1MAPTL3MBTL1SMYD3LOXL2 | |
| SCHEMBL6173009 | 0.72 | SMYD3 (0.51) | ALDH1A1MAPTL3MBTL1SMYD3LOXL2 | |
| SCHEMBL2643689 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1SMYD3LOXL2 | |
| SCHEMBL2643691 | 0.71 | LOXL2 (0.55) | ALDH1A1SMYD3LOXL2 | |
| SCHEMBL27939531 | 0.70 | ALDH1A1 (0.38) | ALDH1A1L3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL1167262 | 0.70 | MEN1 (0.49) | ALDH1A1MAPTL3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101903378-B | Aminotriazole derivatives | ACTELION PHARMACEUTICALS LTD | 2014-03-12 | — | — | CN | claimed |
| CN-101903378-B | Aminotriazole derivatives | ACTELION PHARMACEUTICALS LTD | 2014-03-12 | — | — | CN | disclosed |