Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 2/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | TOP2A | P11388 | 1/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810629 | 0.83 | DHODH (0.32) | DHODH | |
| SCHEMBL28809727 | 0.81 | DHODH (0.31) | DHODHTOP2ATOP2B | |
| SCHEMBL28810746 | 0.72 | DHODH (0.32) | DHODHOPRL1 | |
| SCHEMBL28809785 | 0.72 | OPRL1 (0.34) | DHODHOPRL1 | |
| SCHEMBL29721855 | 0.71 | PIP4K2A (0.31) | TOP2ATOP2B | |
| SCHEMBL28810670 | 0.67 | DHODH (0.33) | DHODHOPRL1 | |
| SCHEMBL28809774 | 0.66 | CPB1 (0.32) | — | |
| SCHEMBL28809781 | 0.63 | ABCB1 (0.31) | DHODHOPRL1 | |
| SCHEMBL28809728 | 0.61 | ESR2 (0.32) | — | |
| SCHEMBL28637340 | 0.56 | ALDH1A1 (0.32) | LMNAOPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |