Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RNF4 | P78317 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28970973 | 0.86 | RNF4 (0.55) | PPARGTSHRMAPTATMALDH1A1 | |
| SCHEMBL9134064 | 0.84 | NR1D1 (0.42) | TSHRMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL9135292 | 0.84 | KEAP1 (0.51) | TSHRRNF4 | |
| SCHEMBL4434199 | 0.84 | SMN1; SMN2 (0.57) | TSHRMAPTATMALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL4434198 | 0.82 | SMN1; SMN2 (0.56) | TSHRMAPTATMALDH1A1KDM4E | |
| SCHEMBL15004697 | 0.80 | PPARG (0.62) | PPARGMAPTALDH1A1KMT2AKDM4E | |
| SCHEMBL28970965 | 0.79 | TSHR (0.45) | PPARGTSHRMAPTATMALDH1A1 | |
| SCHEMBL29194883 | 0.79 | PPARG (0.51) | PPARGMAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL5591533 | 0.79 | PPARG (0.44) | PPARGTSHRMAPTATMALDH1A1 | |
| SCHEMBL29006376 | 0.78 | AOC3 (0.43) | TSHRMAPTALDH1A1SMN1; SMN2RNF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890908-A | Gamma-position trifluoromethyl amino acid derivative and preparation method thereof | 华中科技大学 | 2022-08-12 | — | — | CN | disclosed |