Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4434198 | 0.98 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL6901552 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL7174025 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL20169531 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL11437661 | 0.86 | SMN1; SMN2 (0.59) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL2635519 | 0.84 | SMN1; SMN2 (0.57) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL5967266 | 0.84 | MLYCD (0.48) | SMN1; SMN2GAAALDH1A1TSHRGLA | |
| SCHEMBL5807041 | 0.84 | SMN1; SMN2 (0.60) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL28810656 | 0.84 | PPARG (0.47) | SMN1; SMN2GAAKDM4EALDH1A1TSHR | |
| SCHEMBL9298715 | 0.83 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAALDH1A1TSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012485-A1 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2013-01-10 | — | — | US | disclosed |
| EP-2124913-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | Novartis AG (CH) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008077597-A1 | 1-AMINOMETHYL- L- PHENYL- CYCLOHEXANE DERIVATIVES AS DDP-IV INHIBITORS | NOVARTIS AG (CH) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012485-A1 | ORGANIC COMPOUNDS | DPP4, DPP3, DPP7 | SMN1; SMN2 2612/4885GAA 86/4885KDM4E 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.