SCHEMBL28810922

SCHEMBL28810922

CCC(C)(C(=O)ON1CC=C(c2ccc(C#CCOC)cc2)CC1)S(C)(=O)=O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28810914 0.91 MMP2 (0.33) DRD2DRD4DRD3MMP2MMP3
SCHEMBL28811342 0.88
SCHEMBL28811901 0.87 GABRP (0.34) DRD2DRD4DRD3MMP2MMP3
SCHEMBL28811381 0.86 DRD2 (0.33) DRD2DRD4DRD3MMP2MMP3
SCHEMBL28811338 0.82 MMP2 (0.34) MMP2MMP3PPARGPPARA
Hydrochloric Acid SCHEMBL28810953 0.82 ALDH2 (0.31)
SCHEMBL19989613 0.79 DRD2 (0.40) DRD2DRD4DRD3PPARGPPARA
SCHEMBL28810925 0.78 PPARG (0.43) DRD2DRD4DRD3PPARGPPARA
SCHEMBL28810877 0.76 MMP2 (0.33) MMP2MMP3
SCHEMBL19989694 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110088087-B Tetrahydropyridine derivatives and their use as antibacterial agents 东亚ST株式会社 2022-08-09 CN disclosed