Pyridine

Pyridine

SCHEMBL28811103

Cc1ccc(NCc2ccc(Cl)cc2)cc1.c1ccncc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.60
RAB9A P51151 4/20 0.59
ALDH1A1 P00352 2/20 0.59
MEN1 O00255 3/20 0.53
KMT2A Q03164 3/20 0.53
MAPT P10636 3/20 0.53
KDM4E B2RXH2 2/20 0.53
POLB P06746 2/20 0.53
HSP90AA1 P07900 1/20 0.53
HSP90AB1 P08238 1/20 0.53
GAA P10253 1/20 0.53
THRB P10828 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
MAPK1 P28482 1/20 0.53
CASP1 P29466 1/20 0.53
BLM P54132 1/20 0.53
PLEC Q15149 1/20 0.53
HSD17B10 Q99714 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6416118 0.87 MEN1 (0.67) HTTRAB9AALDH1A1MEN1KMT2A
SCHEMBL10669862 0.87 MEN1 (0.67) HTTRAB9AALDH1A1MEN1KMT2A
SCHEMBL5999682 0.80 KDR (0.59) HTTRAB9AALDH1A1MEN1KMT2A
SCHEMBL171805 0.80 HTT (0.66) HTTRAB9AALDH1A1MEN1KMT2A
SCHEMBL11512612 0.78 MEN1 (0.71) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL10945837 0.78 MEN1 (0.71) RAB9AMEN1KMT2AMAPTKDM4E
SCHEMBL2005375 0.78 MAPT (0.80) HTTRAB9AALDH1A1MEN1KMT2A
SCHEMBL10055032 0.78 MAPT (0.80) HTTRAB9AALDH1A1MEN1KMT2A
SCHEMBL8619703 0.78 ALDH1A1 (0.59) HTTRAB9AALDH1A1MEN1KMT2A
SCHEMBL26102444 0.78 HTT (0.57) HTTRAB9AALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114875434-B Electrochemical method for amination of imine compounds 齐鲁工业大学 2023-08-11 CN disclosed
CN-114875434-A Electrochemical method for amination of imine compound 齐鲁工业大学 2022-08-09 CN disclosed