Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29868526 | 1.00 | SRC (0.51) | SRCPLA2G2ATSHRCYP19A1KMT2A | |
| SCHEMBL28947614 | 0.94 | CYP19A1 (0.57) | SRCPLA2G2ATSHRCYP19A1KMT2A | |
| SCHEMBL9370571 | 0.87 | SRC (0.57) | SRCPLA2G2ATSHRCYP19A1KMT2A | |
| SCHEMBL7970086 | 0.77 | SRC (0.63) | SRCTSHRKMT2AALDH1A1KDM4E | |
| SCHEMBL29337218 | 0.76 | SRC (0.51) | SRCPLA2G2ATSHRCYP19A1KMT2A | |
| SCHEMBL30409139 | 0.74 | PLA2G2A (0.60) | PLA2G2ATSHRCYP19A1KMT2ABRD4 | |
| SCHEMBL31609288 | 0.74 | MEN1 (0.39) | TSHRKMT2AHTR2AALDH1A1 | |
| SCHEMBL24236643 | 0.74 | MEN1 (0.49) | PLA2G2ATSHRKMT2AALDH1A1KDM4E | |
| SCHEMBL7970968 | 0.73 | TSHR (0.47) | SRCPLA2G2ATSHRKMT2AMAPK1 | |
| SCHEMBL4256771 | 0.72 | MEN1 (0.46) | TSHRKMT2AMAPK1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114874251-A | Silicon center chiral silanol and synthetic method thereof | 南方科技大学 | 2022-08-09 | — | — | CN | disclosed |