Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | EDNRB | P24530 | 1/20 | 0.43 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24236617 | 0.80 | TSHR (0.45) | PLA2G2ATSHRMAPTALDH1A1EDNRB | |
| SCHEMBL24236610 | 0.75 | S1PR3 (0.46) | MEN1KMT2ATSHRMAPTALDH1A1 | |
| SCHEMBL28811123 | 0.74 | SRC (0.51) | KMT2APLA2G2ATSHRMAPTALDH1A1 | |
| SCHEMBL29868526 | 0.74 | SRC (0.51) | KMT2APLA2G2ATSHRMAPTALDH1A1 | |
| SCHEMBL24236616 | 0.73 | PLA2G2A (0.58) | MEN1KMT2APLA2G2ATSHRALDH1A1 | |
| SCHEMBL28947614 | 0.69 | CYP19A1 (0.57) | MEN1KMT2APLA2G2ATSHRMAPT | |
| SCHEMBL17469291 | 0.69 | KMT2A (0.56) | MEN1KMT2AL3MBTL1TSHRMAPT | |
| SCHEMBL9370571 | 0.68 | SRC (0.57) | KMT2APLA2G2ATSHRMAPTALDH1A1 | |
| SCHEMBL6527378 | 0.67 | KMT2A (0.62) | MEN1KMT2AL3MBTL1TSHRMAPT | |
| SCHEMBL2864474 | 0.67 | ALDH1A1 (0.61) | MEN1KMT2AL3MBTL1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220031659-A1 | NEUROPROTECTIVE COMPOUNDS AND METHODS OF USE | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220031659-A1 | NEUROPROTECTIVE COMPOUNDS AND METHODS OF USE | SMN1; SMN2, BDNF, PYGB | MEN1 4473/4885KMT2A 3912/4885L3MBTL1 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.