Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 11/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 6/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265127 | 0.75 | MAPK14 (0.58) | PKM | |
| SCHEMBL5266116 | 0.72 | GRM5 (0.44) | MCHR1PKM | |
| SCHEMBL2881979 | 0.72 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL2883772 | 0.70 | MCHR1 (0.56) | MCHR1BCHE | |
| SCHEMBL19746414 | 0.70 | P2RX7 (0.46) | MCHR1L3MBTL1 | |
| SCHEMBL17554285 | 0.70 | EP300 (0.44) | MCHR1L3MBTL1 | |
| SCHEMBL4002396 | 0.68 | MCHR1 (0.82) | MCHR1 | |
| SCHEMBL1366606 | 0.68 | MCHR1 (0.47) | MCHR1PKM | |
| SCHEMBL2884206 | 0.68 | MCHR1 (1.00) | MCHR1BCHE | |
| SCHEMBL1364736 | 0.66 | MCHR1 (0.73) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | MSD K.K. (JP) | 2010-08-26 | — | — | US | disclosed |
| EP-1916239-A1 | PYRIDONE COMPOUND | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-04-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216758-A1 | Pyridone Compounds | NPY1R, MC5R, MC1R | MCHR1 4/4885L3MBTL1 979/4885BCHE 2805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.