Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28784217 | 0.99 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1POLBMAPTHTT | |
| SCHEMBL3513132 | 0.88 | L3MBTL3 (0.57) | L3MBTL3L3MBTL1POLBMAPTHTT | |
| SCHEMBL3513630 | 0.87 | L3MBTL3 (0.56) | L3MBTL3L3MBTL1POLBMAPTHTT | |
| SCHEMBL3511838 | 0.86 | L3MBTL1 (0.54) | L3MBTL3L3MBTL1POLBMAPTHTT | |
| SCHEMBL20456915 | 0.83 | L3MBTL3 (0.59) | L3MBTL3L3MBTL1POLBMAPTHTT | |
| SCHEMBL1354618 | 0.79 | L3MBTL3 (0.62) | L3MBTL3L3MBTL1POLBMAPTHTT | |
| SCHEMBL3639905 | 0.79 | L3MBTL1 (0.65) | L3MBTL3L3MBTL1POLBMAPTHTT | |
| SCHEMBL27720953 | 0.79 | ALDH1A1 (0.43) | POLBMAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL3512031 | 0.79 | GAA (0.64) | L3MBTL1HTTSMN1; SMN2LMNAMEN1 | |
| SCHEMBL17747815 | 0.76 | SMN1; SMN2 (0.61) | L3MBTL3L3MBTL1POLBMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103923072-A | Substituted Indazole Derivatives Active As Kinase Inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2014-07-16 | — | — | CN | disclosed |
| CN-101754956-B | Substituted indazole derivatives active as kinase inhibitors | NERVIANO MEDICAL SCIENCES SRL | 2014-04-23 | — | — | CN | disclosed |