Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.53 |
| ▸ | NOS2 | P35228 | 4/20 | 0.53 |
| ▸ | NOS1 | P29475 | 3/20 | 0.53 |
| ▸ | MET | P08581 | 4/20 | 0.44 |
| ▸ | FEN1 | P39748 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13635718 | 0.86 | NOS3 (0.50) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL4648395 | 0.84 | NOS3 (0.52) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL28811368 | 0.83 | NOS3 (0.47) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL29854857 | 0.83 | NOS3 (0.47) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL28811293 | 0.80 | NOS3 (0.52) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL29860750 | 0.80 | NOS3 (0.52) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL1137172 | 0.79 | NOS3 (0.50) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL28810836 | 0.77 | NOS3 (0.49) | NOS3NOS2NOS1METFEN1 | |
| SCHEMBL1890586 | 0.77 | NOS3 (0.57) | NOS3NOS2NOS1SCN9AMEN1 | |
| SCHEMBL29788816 | 0.77 | NOS3 (0.57) | NOS3NOS2NOS1SCN9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901280-B | MrgprX2 antagonists and uses thereof | 德米拉公司 | 2025-05-27 | — | — | CN | disclosed |
| EP-4054570-A1 | MRGPRX2 ANTAGONISTS AND USES THEREOF | Dermira, Inc (US) | 2022-09-14 | — | — | EP | disclosed |
| CN-114901280-A | MrgprX2 antagonists and uses thereof | 德米拉公司 | 2022-08-12 | — | — | CN | disclosed |