Tetrahydrofuran

Tetrahydrofuran

SCHEMBL28811344

C1CCOC1.Cc1cc(C)cc(I)c1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
LMNA P02545 1/20 0.33
RAB9A P51151 1/20 0.33
TSHR P16473 2/20 0.32
OPRM1 P35372 1/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
HTT P42858 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrofuran SCHEMBL28161889 0.87 ALDH1A1 (0.50) ALDH1A1LMNARAB9ATSHROPRM1
SCHEMBL79108 0.79
Tetrahydrofuran SCHEMBL28535994 0.78 ALDH1A1 (0.40) ALDH1A1LMNARAB9ATSHRSMN1; SMN2
Dioxane SCHEMBL3458161 0.76 ALDH1A1 (0.44) ALDH1A1LMNARAB9ATSHROPRM1
SCHEMBL812374 0.73
M-Xylene SCHEMBL20507015 0.71 ACHE (0.57) ALDH1A1RAB9ATSHRHPGD
P-Xylene SCHEMBL21806075 0.71 ACHE (0.50) ALDH1A1LMNASMN1; SMN2
SCHEMBL213952 0.71 ALDH1A1 (0.40) ALDH1A1LMNATSHROPRM1HPGD
Tetrahydrofuran SCHEMBL5596603 0.70 ALDH1A1 (0.36) ALDH1A1RAB9ASMN1; SMN2
P-Xylene SCHEMBL1332978 0.69 ALDH1A1 (0.47) ALDH1A1LMNARAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103739529-A Synthetic method of phenyl or substituted phenyl terminated long chain fatty thiol SHANXI XINTIANYUAN PHARM & CHEM CO LTD 2014-04-23 CN disclosed