Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 4/20 | 0.30 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810629 | 0.72 | DHODH (0.32) | — | |
| SCHEMBL28810704 | 0.71 | LMNA (0.35) | ABCB1POLBLMNAMEN1KMT2A | |
| SCHEMBL28810667 | 0.70 | LMNA (0.32) | ABCB1LMNATP53NPSR1 | |
| SCHEMBL15520368 | 0.68 | SCD (0.47) | ABCB1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL27266898 | 0.68 | SCD (0.47) | ABCB1LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL16821913 | 0.67 | TOP2A (0.33) | MEN1KMT2ATOP2ATOP2B | |
| SCHEMBL15520260 | 0.65 | SCD (0.49) | CYP11B2 | |
| SCHEMBL28811470 | 0.64 | LMNA (0.38) | LMNATP53NPSR1 | |
| SCHEMBL8339813 | 0.63 | MEN1 (0.40) | POLBMEN1KMT2ACYP11B2 | |
| SCHEMBL8269036 | 0.63 | MEN1 (0.40) | POLBMEN1KMT2ACYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |