Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26268476 | 0.93 | ACHE (0.36) | MAPTPOLBACHEALDH1A1TSHR | |
| SCHEMBL8139572 | 0.87 | SLC18A3 (0.39) | ALDH1A1ABCB1SLC18A3GAA | |
| SCHEMBL13783352 | 0.85 | — | — | |
| SCHEMBL26269430 | 0.74 | GAA (0.40) | GAA | |
| SCHEMBL28810670 | 0.71 | DHODH (0.33) | — | |
| SCHEMBL8339813 | 0.71 | MEN1 (0.40) | MAPTPOLBACHEALDH1A1TSHR | |
| SCHEMBL8269036 | 0.71 | MEN1 (0.40) | MAPTPOLBACHEALDH1A1TSHR | |
| SCHEMBL8143998 | 0.71 | OPRK1 (0.30) | — | |
| SCHEMBL28811466 | 0.71 | ABCB1 (0.33) | LMNATP53NPSR1POLBABCB1 | |
| SCHEMBL28811470 | 0.69 | LMNA (0.38) | LMNATP53NPSR1MAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |