Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28810398 | 0.86 | ABCB1 (0.35) | ABCB1HTT | |
| SCHEMBL28811470 | 0.81 | LMNA (0.38) | LMNATP53NPSR1 | |
| SCHEMBL28810635 | 0.73 | PKM (0.35) | LMNATP53NPSR1 | |
| SCHEMBL28811463 | 0.71 | — | — | |
| SCHEMBL28811466 | 0.70 | ABCB1 (0.33) | LMNATP53NPSR1ABCB1 | |
| SCHEMBL28810402 | 0.67 | ALDH1A1 (0.33) | LMNAKDM4E | |
| SCHEMBL19626479 | 0.67 | ALDH1A1 (0.33) | LMNAKDM4E | |
| SCHEMBL28810749 | 0.65 | CDK5 (0.33) | LMNAKDM4E | |
| SCHEMBL28809769 | 0.63 | MEN1 (0.36) | LMNANPSR1HTT | |
| SCHEMBL28810606 | 0.63 | SLC18A3 (0.32) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746090-A | Azaindole carboxamide compounds for the treatment of mycobacterial infections | 结核病药物开发全球联盟公司 | 2022-07-12 | — | — | CN | disclosed |