Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | LYN | P07948 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597804 | 0.81 | POLB (0.41) | CXCR2HPGDMAPK1CDK2NPC1 | |
| SCHEMBL12100569 | 0.81 | NOS2 (0.47) | CXCR2HPGDMAPK1CDK2NPC1 | |
| SCHEMBL21056547 | 0.81 | DHODH (0.51) | CXCR2AURKAMAPTGAAPDE4A | |
| SCHEMBL24776313 | 0.79 | MEN1 (0.52) | HPGDMAPK1CDK2NPC1RAB9A | |
| SCHEMBL8014673 | 0.74 | ALDH1A1 (0.61) | CXCR2HPGDMAPK1RAB9AMAPT | |
| SCHEMBL5133830 | 0.73 | KMT2A (0.50) | HPGDMAPK1CDK2NPC1RAB9A | |
| SCHEMBL28754176 | 0.71 | HPGD (0.48) | CXCR2HPGDMAPK1MAPTKDM1A | |
| SCHEMBL28067022 | 0.71 | NOS2 (0.41) | CYP2A6 | |
| SCHEMBL24318169 | 0.71 | ALDH1A1 (0.62) | CXCR2HPGDMAPK1ATMMAPT | |
| SCHEMBL16919139 | 0.71 | ALDH1A1 (0.49) | HPGDHSD17B10ALDH1A1GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109535155-B | Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases | 艾伯维公司 | 2022-07-12 | — | — | CN | disclosed |