Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MARK3 | P27448 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28811513 | 0.81 | CXCR2 (0.42) | POLBCXCR2MAPTMAPK1CHEK1 | |
| SCHEMBL12100569 | 0.79 | NOS2 (0.47) | CXCR2MAPTMAPK1CHEK1IKBKB | |
| SCHEMBL28015638 | 0.77 | RAB9A (0.43) | POLBMAPTNPC1RAB9AMEN1 | |
| SCHEMBL23240442 | 0.75 | PIK3C3 (0.38) | NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL19552432 | 0.73 | NOS2 (0.39) | MEN1KMT2AALDH1A1 | |
| SCHEMBL3224534 | 0.73 | CCR1 (0.35) | — | |
| SCHEMBL9980898 | 0.73 | ATR (0.42) | POLBMAPTNPC1RAB9AKMT2A | |
| SCHEMBL31695932 | 0.72 | PIN1 (0.52) | POLBCXCR2MAPTMAPK1NPC1 | |
| SCHEMBL8014673 | 0.72 | ALDH1A1 (0.61) | CXCR2MAPTMAPK1RAB9AHPGD | |
| SCHEMBL14618510 | 0.72 | PTGS2 (0.53) | CXCR2MAPTMAPK1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007010352-A1 | AN IMPROVED PROCESS FOR INDUSTRIAL MANUFACTURE OF NEVIRAPINE | EMCURE PHARMACEUTICALS LIMITED (IN) | 2007-01-25 | — | — | WO | disclosed |