SCHEMBL28811523

SCHEMBL28811523

Nc1ccc(CO)cc1.OBO

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
ALDH1A1 P00352 2/20 0.50
CYP3A4 P08684 2/20 0.50
GFER P55789 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.48
PRSS1 P07477 1/20 0.44
PRSS2 P07478 1/20 0.44
PRSS3 P35030 1/20 0.44
CA6 P23280 2/20 0.43
CA14 Q9ULX7 2/20 0.43
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA4 P22748 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA9 Q16790 1/20 0.43
CA5B Q9Y2D0 1/20 0.43
MAOB P27338 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL54121 0.92
Hydrochloric Acid SCHEMBL864912 0.89 ALDH1A1 (0.55) TSHRALDH1A1CYP3A4GFERTDP1
SCHEMBL1309905 0.84 CYP3A4 (0.58) TSHRALDH1A1CYP3A4GFERTDP1
Bicarbonate SCHEMBL932925 0.82 TSHR (0.48) TSHRALDH1A1CYP3A4GFERTDP1
SCHEMBL18364910 0.78 ALDH1A1 (0.44) TSHRALDH1A1CYP3A4GFERTDP1
SCHEMBL12653890 0.78 MAPT (0.64) TSHRALDH1A1CYP3A4GFERTDP1
SCHEMBL23748641 0.78 LTA4H (0.65) TSHRALDH1A1CYP3A4GFERTDP1
SCHEMBL15836247 0.78 MAPT (0.54) TSHRALDH1A1CYP3A4GFERTDP1
SCHEMBL12973296 0.78 APP (0.58) TSHRALDH1A1CYP3A4GFERTDP1
SCHEMBL41775 0.76 TSHR (0.67) TSHRPRSS1PRSS2PRSS3CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113136020-B Water-based polyurethane polymer and preparation method thereof, single-component water-based polyurethane waterproof coating and preparation method and application thereof 万华化学集团股份有限公司 2022-08-05 CN claimed