Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | PREP | P48147 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22233965 | 0.81 | PREP (0.52) | ATMPREPCTSKCTSLCTSB | |
| SCHEMBL28169365 | 0.81 | PREP (0.52) | ATMPREPCTSKCTSLCTSB | |
| SCHEMBL30101231 | 0.79 | P2RX7 (0.51) | CTSKCTSLCTSBCTSSCCR1 | |
| SCHEMBL16333011 | 0.79 | CTSL (0.53) | ATMPREPCTSKCTSLCTSB | |
| SCHEMBL30101252 | 0.79 | SYK (0.48) | ATMPREPCTSKCTSLCTSB | |
| SCHEMBL6323614 | 0.79 | CTSL (0.50) | ATMPREPCTSKCTSLCTSB | |
| SCHEMBL29041528 | 0.76 | ATM (0.46) | ATMPREPCTSKCTSLCTSB | |
| SCHEMBL8028197 | 0.75 | MEN1 (0.61) | TSHR | |
| SCHEMBL6841175 | 0.74 | ATM (0.58) | ATMCTSKCTSLCTSBCTSS | |
| SCHEMBL14805806 | 0.74 | ALDH1A1 (0.60) | CTSKCTSLCTSBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107072205-B | SMYD inhibitors | EPIZYME股份有限公司 | 2022-07-15 | — | — | CN | disclosed |