Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.44 |
| ▸ | NOS2 | P35228 | 5/20 | 0.44 |
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560281 | 0.84 | NOS1 (0.43) | NOS1NOS2NOS3ALDH1A1USP30 | |
| SCHEMBL28811197 | 0.84 | USP30 (0.46) | NOS1NOS2NOS3USP30SYK | |
| SCHEMBL17560179 | 0.83 | NOS1 (0.44) | NOS1NOS2NOS3USP30SYK | |
| SCHEMBL17591733 | 0.82 | USP30 (0.57) | USP30PDE4BWNT3A | |
| SCHEMBL23090047 | 0.82 | BUB1 (0.47) | USP30PDE4BWNT3A | |
| SCHEMBL29736513 | 0.82 | BUB1 (0.47) | USP30PDE4BWNT3A | |
| SCHEMBL26126144 | 0.82 | IRAK4 (0.48) | NOS1NOS2NOS3 | |
| SCHEMBL18497654 | 0.81 | NOS2 (0.54) | NOS2USP30 | |
| SCHEMBL30585858 | 0.81 | NOS2 (0.54) | NOS2USP30 | |
| SCHEMBL18689602 | 0.77 | PDE4B (0.46) | USP30PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028619-A | SMYD inhibitors | EPIZYME股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| CN-107072205-B | SMYD inhibitors | EPIZYME股份有限公司 | 2022-07-15 | — | — | CN | disclosed |