Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 6/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.43 |
| ▸ | NOS2 | P35228 | 4/20 | 0.43 |
| ▸ | NOS3 | P29474 | 2/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17560179 | 0.85 | NOS1 (0.44) | USP30NOS1NOS2NOS3SYK | |
| SCHEMBL26126144 | 0.84 | IRAK4 (0.48) | HCRTR1HCRTR2NOS1NOS2NOS3 | |
| SCHEMBL28811698 | 0.84 | NOS1 (0.44) | USP30NOS1NOS2NOS3SYK | |
| SCHEMBL17560281 | 0.84 | NOS1 (0.43) | USP30NOS1NOS2NOS3SYK | |
| SCHEMBL30585858 | 0.83 | NOS2 (0.54) | USP30NOS2ACHEGPR119POLB | |
| SCHEMBL18497654 | 0.83 | NOS2 (0.54) | USP30NOS2ACHEGPR119POLB | |
| SCHEMBL25984948 | 0.82 | GPR119 (0.45) | USP30FPR3FPR2EHMT2GPR119 | |
| SCHEMBL17591884 | 0.81 | USP30 (0.56) | USP30FPR3FPR2KRAS | |
| SCHEMBL30568428 | 0.81 | HCRTR2 (0.47) | USP30HCRTR1HCRTR2NOS1NOS2 | |
| SCHEMBL25609008 | 0.79 | PTPN2 (0.59) | USP30GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028619-A | SMYD inhibitors | EPIZYME股份有限公司 | 2022-09-09 | — | — | CN | disclosed |
| WO-2022173849-A1 | (HETERO)ARYLAMINO-CYCLOHEXYL-SULFONYL DERIVATIVES AS CCR6 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-08-18 | — | — | WO | disclosed |
| CN-107072205-B | SMYD inhibitors | EPIZYME股份有限公司 | 2022-07-15 | — | — | CN | disclosed |