SCHEMBL28811861

SCHEMBL28811861

CC(C)(CI)c1ccccc1Br

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA5A P35218 1/20 0.37
CA9 Q16790 1/20 0.37
ALDH1A1 P00352 2/20 0.36
PLCG1 P19174 1/20 0.33
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TAAR1 Q96RJ0 4/20 0.31
CA4 P22748 1/20 0.31
CA6 P23280 1/20 0.31
HSD11B1 P28845 1/20 0.31
RIPK1 Q13546 1/20 0.31
PYCR1 P32322 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10608749 0.80 RIPK1 (0.39) CA1CA2CA5ACA9ALDH1A1
SCHEMBL28812269 0.78 CA1 (0.41) CA1CA2CA5ACA9ALDH1A1
SCHEMBL5846484 0.78 TAAR1 (0.50) CA1CA2CA5ACA9ALDH1A1
SCHEMBL12317693 0.78 CA2 (0.37) CA1CA2CA5ACA9ALDH1A1
SCHEMBL23954525 0.77 ALDH1A1 (0.44) CA2ALDH1A1TSHRTDP1TAAR1
SCHEMBL19222142 0.77 CA1 (0.36) CA1CA2CA5ACA9ALDH1A1
SCHEMBL9248186 0.75 CA1 (0.35) CA1CA2CA5ACA9ALDH1A1
SCHEMBL28749067 0.75 CA2 (0.41) CA1CA2CA5ACA9ALDH1A1
SCHEMBL9275642 0.74 ALDH1A1 (0.43) CA1CA2CA5ACA9ALDH1A1
SCHEMBL5080120 0.74 ALDH1A1 (0.43) CA1CA2CA5ACA9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114920758-B Luminescent material, application thereof and organic electroluminescent device comprising luminescent material 清华大学 2024-09-06 CN disclosed
CN-116789589-A Chiral aza spiro compound and preparation method and application thereof 北京理工大学 2023-09-22 CN disclosed
CN-114920758-A Luminescent material, application thereof and organic electroluminescent device comprising luminescent material 清华大学 2022-08-19 CN disclosed