Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16409448 | 0.98 | OPRM1 (0.54) | OPRM1TP53TRPV1TRPA1ALDH1A1 | |
| SCHEMBL13472086 | 0.84 | — | — | |
| SCHEMBL6716581 | 0.84 | GPR84 (0.42) | TRPV1TRPA1SPHK1TSHRGPR84 | |
| SCHEMBL28578505 | 0.84 | GPR84 (0.42) | TRPV1TRPA1SPHK1TSHRGPR84 | |
| SCHEMBL28576044 | 0.84 | GPR84 (0.42) | TRPV1TRPA1SPHK1TSHRGPR84 | |
| SCHEMBL27869316 | 0.82 | TRPV1 (0.39) | OPRM1TP53TRPV1TRPA1SPHK1 | |
| SCHEMBL23530055 | 0.81 | GPR84 (0.46) | TRPV1TRPA1SPHK1TSHRGPR84 | |
| SCHEMBL30787307 | 0.81 | GPR84 (0.46) | TRPV1TRPA1SPHK1TSHRGPR84 | |
| SCHEMBL30787291 | 0.81 | GPR84 (0.46) | TRPV1TRPA1SPHK1TSHRGPR84 | |
| SCHEMBL30787116 | 0.81 | GPR84 (0.46) | TRPV1TRPA1SPHK1TSHRGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103724261-A | Novel industrial production method for hydroxychloroquine sulfate | WUHAN WUYAO PHARMACEUTICAL CO LTD | 2014-04-16 | — | — | CN | claimed |
| CN-103724261-B | A kind of industrialized process for preparing of hydroxychloroquine sulfate quinoline | WUHAN WUYAO PHARMACEUTICAL CO., LTD. (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-103724261-B | A kind of industrialized process for preparing of hydroxychloroquine sulfate quinoline | WUHAN WUYAO PHARMACEUTICAL CO., LTD. (CN) | 2016-05-25 | — | — | CN | disclosed |
| CN-103724261-A | Novel industrial production method for hydroxychloroquine sulfate | WUHAN WUYAO PHARMACEUTICAL CO LTD | 2014-04-16 | — | — | CN | disclosed |