Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825848 | 0.78 | — | — | |
| SCHEMBL27825880 | 0.76 | — | — | |
| SCHEMBL27911631 | 0.72 | ERCC1 (0.32) | — | |
| SCHEMBL27983037 | 0.72 | — | — | |
| SCHEMBL27965699 | 0.71 | SLC6A3 (0.37) | — | |
| SCHEMBL27638202 | 0.68 | TAAR1 (0.32) | — | |
| SCHEMBL27827444 | 0.66 | — | — | |
| SCHEMBL27666655 | 0.66 | ESR1 (0.33) | — | |
| SCHEMBL27992365 | 0.66 | ALDH1A1 (0.36) | LMNAMAPT | |
| SCHEMBL6037437 | 0.65 | ALDH1A1 (0.41) | LMNAMAPTTTKAURKBINCENP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101987848-B | New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing the same | SERVIER LAB | 2014-06-18 | — | — | CN | disclosed |