Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27825848 | 0.77 | — | — | |
| SCHEMBL260550 | 0.75 | SLC6A3 (0.44) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 | |
| SCHEMBL261027 | 0.74 | SLC6A3 (0.43) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 | |
| SCHEMBL28812170 | 0.71 | LMNA (0.33) | — | |
| SCHEMBL27825880 | 0.71 | — | — | |
| SCHEMBL27983037 | 0.68 | — | — | |
| SCHEMBL27911631 | 0.68 | ERCC1 (0.32) | — | |
| SCHEMBL64778 | 0.68 | HRH3 (0.39) | HRH3L3MBTL1TDP1 | |
| Ethoxycarbonyl Group SCHEMBL27965698 | 0.68 | HRH3 (0.42) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 | |
| SCHEMBL1225211 | 0.67 | DAO (0.51) | SLC6A3HRH3L3MBTL1SIGMAR1MBTD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101987848-B | New dihydroindolone derivatives, method of preparing same and pharmaceutical compositions containing the same | SERVIER LAB | 2014-06-18 | — | — | CN | disclosed |