Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2A13 | Q16696 | 4/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25818344 | 0.82 | KCNK3 (0.34) | HSD17B10CYP2A13MEN1ALDH1A1KMT2A | |
| SCHEMBL25817832 | 0.69 | MAPT (0.35) | HSD17B10MEN1KMT2ANPC1MAPT | |
| SCHEMBL15166031 | 0.66 | ABCB1 (0.38) | HRH3ALDH1A1KMT2AMAPT | |
| SCHEMBL30791523 | 0.66 | KDM4E (0.38) | ALOX15HSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL6703722 | 0.63 | LMNA (0.48) | ALOX15HSD17B10CYP2A13MEN1ALDH1A1 | |
| SCHEMBL29867907 | 0.62 | KDM4E (0.30) | ALDH1A1HTT | |
| SCHEMBL16467921 | 0.59 | — | — | |
| SCHEMBL6852012 | 0.58 | LMNA (0.52) | ALOX15HSD17B10MEN1ALDH1A1KMT2A | |
| SCHEMBL4425954 | 0.57 | SIGMAR1 (0.53) | CYP2A13HRH3MEN1ALDH1A1KMT2A | |
| SCHEMBL4754 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169281-A | Fused pyrroledicarboxamides and their use as pharmaceuticals | SANOFI SA | 2014-11-26 | — | — | CN | disclosed |